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MCP servers
Pharmaceutical Regulatory Intelligence
Comprehensive pharmaceutical regulatory intelligence MCP server. 4 tools across 7 databases and 45,000+ records. Look up drugs across DrugBank (4,947 compounds), WHO Essential Medicines (782), Australian TGA (23,259 registered medicines), and FDA NDI notifications (1,330). Check drug-drug interactions (5,000 documented interactions) with severity grouping. Query FDA FAERS adverse event reports (2,000 top drugs). Full-text search across all pharmaceutical databases including ChEMBL bioactivity (7,941 records). Built by Two Halves — twohalves.ai
Follow the source guide for connection and authentication details.
Available tools
check_drug
Check a drug, medicine, active ingredient, or CAS number across pharmaceutical safety and regulatory datasets. Use when the user asks for DrugBank details, WHO Essential Medicines status, Australian TGA records, FDA NDI notifications, targets, dosage forms, indications, or regulatory lookup for a specific substance. Do not use for drug-drug interaction pair checks, FAERS adverse-event signal summaries, broad disease/topic discovery, or cosmetic/food/cannabis substances. The response includes identifiers, compound metadata, targets, schedules, dosage forms, indications, and regulatory records from matched datasets.
check_drug_interactions
Check drug-drug interactions for one medication or a specific two-drug pair. Use when the user asks whether warfarin and aspirin interact, wants interaction severity, mechanism, clinical effect, evidence, or management guidance for medication safety review. Do not use for general drug monographs, adverse-event frequency, regulatory status, or non-drug ingredient interactions. The response includes matching interaction pairs, severity, mechanism, clinical effect, evidence level, and management recommendations.
check_adverse_events
Check FDA FAERS adverse-event records for a drug or active ingredient. Use when the user asks about reported side effects, serious outcomes, death reports, top reactions, age distribution, or post-market safety signals for a medication. Do not use for interaction mechanisms, regulatory approval lookup, nutrition/supplement advice, or adverse events not tied to a drug name. The response includes report totals, serious outcome counts, death counts, top adverse reactions, and common patient age groups.
search_pharma
Search pharmaceutical regulatory and safety datasets by disease, drug class, endpoint, indication, or safety keyword. Use when the user needs broad discovery across DrugBank, WHO Essential Medicines, TGA ARTG, FAERS, FDA NDI, interactions, or ChEMBL before choosing a specific drug tool. Do not use for exact drug monographs, two-drug interaction checks, or FAERS summaries when the drug name is already known. The response includes cross-dataset matches with dataset labels, names, identifiers, snippets, and source-specific fields.